KryptoScanTM: 81Rb/81mKr Generator
KryptoScanTM is a radionuclide generator. The mother-radionuclide (Rubidium-81) is immobilized on a membrane, through which the daughter radionuclide (krypton-81m) is eluted with the passing of air.
Krypton-81m is ideally suited for lung ventilation studies. Its very short half-life results in a low radiation burden for the patient. With a gamma energy higher than that of 99mTc, it enables lung ventilation studies to be performed immediately after a perfusion study of the pulmonary vascular bed.
- Packaging: Radionuclidic generator.
- Availability: Dispensed daily.
- Calibration: 12:00 p.m. CET at day after production.
Fact Sheet: KryptoScanTM: 81Rb/81mKr GeneratorDownload
|Pharmaceutical form||Radionuclidic generator|
|Available quantities||75 – 740 MBq per generator at calibration|
|Expiry||20 hours from time of calibration|
|Radionuclide purity||81Rb breakthrough: <50 Bq/GBq/L 81mKr|
KryptoScanTM is a radionuclide generator. It functions by the passing of environmental air over a mother-radionuclide – Rubidium-81 (81Rb) – immobilized on a membrane. This results in elution of the daughter-radionuclide, Krypton-81 (81mKr).
81mKr, an inert gas, is ideally suited for lung ventilation studies in nuclear medicine. The very short half-life of 81mKr (13 seconds) results in a low radiation burden for the patient.
The gamma energy of 81mKr is higher than that of 99mTc. This enables the performance of lung ventilation studies immediately after a vascular pulmonary bed perfusion study with intravenously injected 99mTc macroaggregated albumin, without interference of the 99mTc gamma-rays throughout the study.
BV Cyclotron VU is a global health science company that produces radiopharmaceuticals and radiochemicals for medical diagnostics and research. Located at the campus of VU University Medical Center in Amsterdam, BV Cyclotron VU produces GMP-compliant medical isotopes in state-of-the-art manufacturing facilities. They are used daily by pharmaceutical and biotechnological companies, medical device manufacturers, hospitals, clinics, and research laboratories.
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